What The Liposomal Encapsulation Means To Clinical Therapy

By Kristen Baird


The use of liposome in clinical medicine first came to trial in the 1960s, and research and clinical trials that have since followed made sure that this amazing technological evolution can now be applied for both clinical therapy and in other aspect of life. However, the liposomal encapsulation technology (LET) is still in its early stages of development, with little information known to the wider public.

There is a general concurrence in the field of medicine and in the area of science as a whole that LET is the technology that is most likely to replace the capsule, needles, serum, and tablets as the most preferred method of drug administration. The clinical trials have demonstrated with no doubt that LET offers a unique solution in the treatment of racehorse with no need of needles.

The technology uses phospholipid film or liposome to encase the desired compounds and transport them safely through the gastrointestinal tract without exposing the content to the environmental factors like the moisture, the enzymes, the salts and any other substance within body tissues. Currently, the technology has attracted other users apart from the pharmacists. The beauty product industries and the supplement industries are now turning to LET as an alternative to the conventional methods previously used for the administration of these substances into the body tissues.

Phospholipid liposome is used come up with a defense that is capable of repelling the negative impacts that can result from the body radicals, digestive juices, the alkaline solutions, and even salts. Since the protection only lasts when the compounds are on the way to their target to the moment they reach the targeted tissue, the cells in the targeted tissue immediately allows the compound in and transfers the same into the intracellular space making the method so effective.

The liposomes easily penetrate the cell walls of most living tissues; thereby turning out to be an effective weapon against most pathogens that are disease causing. Its effectiveness is also very highly rated with research findings indicating that 50 grams of Vitamin C delivered directly into the tissue is only as effective as 5 grams of the same delivered through the LET.

Clearly, the advantages of LET over the other forms of drug delivery are many. It allows nutrients to transport power packed natural compounds to the targeted tissues and organs without discomposing the same. This makes a lot of medical and economic sense. Normally, the drugs would be affected by a number of environmental factors as they pass to the tissues. These include oxygen, moisture, differing pH, and enzymes among others. This in addition to factors that affect absorption of nutrients into the body, such as fillers, sugars, binders, and sugar can cause a problem due to incomplete absorption.

The introduction of phospholipids into the body also comes with its advantages, the most common one being its anti aging properties. This is through its ability to cut down on serum lipids, decrease bad cholesterol, increase good cholesterol, and amplify red blood cell fluidity, decrease platelet aggregation, and triglyceride. It is also known to boost immunity, memory quality, exercise tolerance and offers liver protection among several other benefits.

Even with all these potential advantages, the studies are not conclusive of the safety of this technology. It is also advisable to design the most effective drug administration that is a cocktail of this and other conventional methods that have been used for centuries to attain the best results.




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